Yes. When using the WooCommerce Bookings and WooCommerce Product Vendors plugins the listing owner can manage the availability of the booking times, from within the WordPress / WooCommerce vendor management backend.
More details on WooCommerce Booking + Product Vendors can be found on the respective sales pages.
Disclaimer: The vendor plugins mentioned in this article display the WordPress backend to the vendor when managing bookings. This is a limitation of the plugins.
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